Project Title: The Brain and Emotion: Neuroimaging Faculty Name: Shackman, Alex Project Description:
TEACHING AND MENTORSHIP:
The overarching mission of the lab is to have a deep impact on the
fields of affective and translational neuroscience. To that end, we do
our best to perform innovative studies that can lead to important
discoveries, to disseminate our discoveries as widely as possible, and
to mentor trainees to become top-notch scientists. My aim is to
understand the interplay of emotion and cognition, with a particular
focus on characterizing the impact of individual differences in anxiety
on attention, memory, and cognitive control. Most of our research is
geared toward identifying the mechanisms that link high levels of
anxiety to the development of psychopathology, including the
identification of novel brain-based biomarkers and transdiagnostic
endophenotypes. If you are looking for a lab to join as an undergraduate
research assistant, please email shackman@umd.edu .
We are always looking for people who are smart, productive, sensible,
passionate, rigorous, fearless in the face of technical and logistical
challenges, hardworking, blessed with a creative vision, and who can
actively contribute to a positive lab environment (fun!). The lab
provides an excellent opportunity for receiving top-notch mentorship in
affective/translational neuroscience. My goal is to ensure that all of
my trainees are happy and cultivate the range of skills necessary to
secure positions at top-tier universities. We are especially interested
in students with expertise in programming, computer science, electrical
engineering, IT, or Matlab.
RESEARCH OVERVIEW:
Anxiety disorders are a leading source of suffering in children and
adults. These disorders first emerge early in life, are extremely
common, and often resist treatment. Individuals with an anxious
temperament -- those who express anxiety too intensely or in
inappropriate contexts -- are much more likely to develop anxiety and
other serious psychiatric disorders, including depression and substance
abuse. To understand the substrates of this liability, we use a broad
spectrum of tools, including multimodal brain imaging, peripheral
physiological measures, and behavioral assays. Our laboratory is
particularly focused on characterizing the mechanisms by which anxiety
alters the processing of threats and punishments in a way that enhances
the likelihood of maladaptive avoidance and behavioral inhibition.
Clinically, this work promises to enhance our understanding of how
emotional traits and states modulate risk, facilitate the discovery of
novel endophenotypes and biomarkers, and set the stage for developing
improved interventions. From a basic psychological science perspective,
our research begins to address fundamental questions about the interplay
of emotion and cognition and the nature of personality.
RESEARCH THEMES:
Dr. Shackman's major research interests include affective and cognitive
neuroscience; neural bases of threat processing, anxiety, fear, and
their application to anxiety, mood, and related psychiatric disorders;
neural bases of personality and individual differences in anxiety and
behavioral inhibition; cognition × emotion interactions: interactions of
anxiety and higher cognition (cognitive control, selective attention,
and working memory); developmental psychopathology; amygdala; anterior
cingulate cortex (ACC); prefrontal cortex (PFC).
KEY METHODS:
Key methods used by our lab include multimodal neuroimaging (fMRI, PET,
VBM); electrophysiological techniques (ERP/EEG, LORETA source
modeling), peripheral physiological techniques (cortisol, facial EMG,
fear-potentiated startle), and behavioral assays (economic games and
experience sampling). Populations of interest include children,
adolescents, healthy adults, and psychiatric patients.
BACKGROUND:
Dr. Shackman received his Ph.D. in Biological Psychology with a
distributed minor in Neuroscience from the University of
Wisconsin-Madison in 2008. His graduate research was supported by the
National Science Foundation and National Institute of Mental Health. He
subsequently conducted postdoctoral research in the laboratories of
Richard Davidson, Brad Postle, and Ned Kalin in the Departments of
Psychology and Psychiatry at Wisconsin. He serves as an Associate Editor
at Cognition and Emotion; Frontiers in Human Neuroscience; and
Cognitive, Affective & Behavioral Neuroscience (CABN). Dr. Shackman
joined the faculty at UMD in the summer of 2013.
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